Cassino (Italian pronunciation: [kassino]) is a comune in the province of Frosinone, Southern Italy, at the southern end of the region of Lazio, the last city of the Latin Valley.

Cassino, town, Lazio (Latium) regione, central Italy.

Cassino. / (Italian kassino) / noun. a town in central Italy, in Latium at the foot of Monte Cassino: an ancient Volscian (and later Roman) town and citadel.